Essential features of REFMAC5
REFMAC5 is a ML FFT program for the refinement of macromolecular structures
- Multiple tasks (phased and non-phased restrained, unrestrained, rigid-body refinement, idealization)
- Fast convergence (approximate 2nd-order diagonal minimization)
- Extensive built-in dictionary (LIBCHECK)
- Graphical control (CCP4i)
- Flexible parameterization (iso-,aniso-,mixed-ADPs, TLS, bulk solvent)
- Easy to use (coordinate and reflection files, straightforward inclusion of alternate conformations)