M.I.R.(A.S.)
The only generally applicable way of solving macromolecular crystal structure
Problems
Stages
Techniques
Data collection
Scaling
Comparison
Difference Pattersons
Difference Patterson
Non-isomorphism
Solving HA sub-structure
Shelxs input
Shelxs solution
Checking Solution
Refinement of solution
Cross/self phasing
Cross phasing of 2nd derivative
Refinement of sites
Refinement of all derivatives
Initial phasing
Initial phases
Initial (MIRAS) map
Density Modification
Solvent flattening
Solvent flattened map
NCS averaging
NCS averaged (phase extended) map
Phase Extension
Associated/Related methods
Example used
Email: a.w.ashton@dl.ac.uk
Home Page: http://www.ccp4.ac.uk