README AFTER YOU READ the README file!!!

This distribution of MOSFLM v6.0 is slightly different from previous editions, as it includes the build for the Rossmann Fourier Auto-indexing routines, which are written mainly in C. You should be aware that there are some minor modifications to the RFA routines, so don't be tempted to install updates blindly from the Purdue site!

The program has been built successfully on the following machines; the "build times" refer to elapsed time while the machine has a typical load of users - in the case of the SGIs and the PC, that's one or two people; for the Alpha, it's nearer 40.

The Makefile in the top directory has checks for the environment variables PWD and HOSTTYPE; the different builds are all included in files in sub-directories according to the host type. You shouldn't need to touch the Makefiles at all, I hope (problems to the usual address...).


     Platform                          O/S              build time (min)
Alpha 275MHz, 1Gb                Digital UNIX               ~10
SGI 200MHz R4010/4400, 64Mb      Irix 5.3 (-Olimit unset)    ~8
SGI 175MHz R10000/R10010, 192Mb  Irix 6.2 (-Olimit unset)    ~4
 "    "        "     "      "      "   "  (-Olimit 3400)    ~18
PC 233MHz pentium, 128Mb         Red Hat Linux 5.1           ~7

The build will involve a lot of paging if your machine has limited RAM, as will running the program. The executable is ~3.0 - 3.6Mb, and integrating a single 8Mb image uses up to around 16Mb, so I'd guess that 32Mb RAM is about the minimum you'd want to use.



INSTALLATION


The main impetus behind this new version is the incorporation of the Rossmann/ Steller Fourier auto-indexing routine, which is much more robust than the previous method (REFIX) and requires only a single image; however, both methods are retained to enhance choice. The new auto-indexing is the default, and needs an estimate of the maximum expected cell edge; a value of 200 Angstroms is supplied, which seems to work for most cells in the range 50 - 240 Angstroms.

If you are a new user of MOSFLM and would like the option of using REFIX, you should e-mail Andrew Leslie and ask for it.


Harry Powell, MRC-LMB, MRC Centre, Hills Road, Cambridge, U.K. CB2 2QH harry@mrc-lmb.cam.ac.uk
Last modified: Fri Jul 9 17:09:39 MET DST 1999